Age-Related Histological Changes in Kidneys of Brown Norway Rat

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Age-Related Histological Changes in Kidneys of Brown Norway Rat

In this study, age-dependent histological changes in the kidneys of Brown Norway rat, a strain useful for conducting aging research, were evaluated. Examination was performed at 3, 12, 18, 24 and 30 months of age. Sclerotic and hypertrophic changes of the glomeruli were observed, and quantitative scores of these changes persistently increased with age. A marginal increase in scores was observed...

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Age-related changes in cardiac structure and function in Fischer 344 Brown Norway hybrid rats

Hacker, Timothy A., Susan H. McKiernan, Pamela S. Douglas, Jonathan Wanagat, and Judd M. Aiken. Age-related changes in cardiac structure and function in Fischer 344 Brown Norway hybrid rats. Am J Physiol Heart Circ Physiol 290: H304–H311, 2006. First published September 2, 2005; doi:10.1152/ajpheart.00290.2005.— The effects of aging on cardiovascular function and cardiac structure were determin...

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Age-related changes in cardiac structure and function in Fischer 344 x Brown Norway hybrid rats.

The effects of aging on cardiovascular function and cardiac structure were determined in a rat model recommended for gerontological studies. A cross-sectional analysis assessed cardiac changes in male Fischer 344 x Brown Norway F1 hybrid rats (FBN) from adulthood to the very aged (n = 6 per 12-, 18-, 21-, 24-, 27-, 30-, 33-, 36-, and 39-mo-old group). Rats underwent echocardiographic and hemody...

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Impaired myogenic autoregulation in kidneys of Brown Norway rats.

The Brown Norway (BN) rat is normotensive and has an extended lifespan but is extremely sensitive to hypertension-induced renal injury. Relative impairment of autoregulation has been implicated in the progression of renal failure whereas absence of myogenic autoregulation is associated with early renal failure. Therefore, we tested the hypothesis that there is conditional failure of renal autor...

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histological changes of the kidneys in iron deficiency anemia

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ژورنال

عنوان ژورنال: Journal of Veterinary Medical Science

سال: 2014

ISSN: 0916-7250,1347-7439

DOI: 10.1292/jvms.13-0431